Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.54 |
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.48 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.46 |
| ▸ | MGAM | O43451 | 1/20 | 0.43 |
| ▸ | P4HA1 | P13674 | 2/20 | 0.42 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | MIF | P14174 | 1/20 | 0.41 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2922164 | 0.83 | NAPRT (0.39) | TTRHCAR2NAPRTTSHRSRD5A2 | |
| SCHEMBL9195960 | 0.82 | CA5A (0.40) | TTRNAPRTTPMTALDH1A1MEN1 | |
| SCHEMBL232290 | 0.81 | HCAR2 (0.50) | TTRHCAR2NAPRTTSHRSRD5A2 | |
| SCHEMBL29365646 | 0.81 | HCAR2 (0.50) | TTRHCAR2NAPRTTSHRSRD5A2 | |
| SCHEMBL3650453 | 0.79 | HCAR2 (0.48) | TTRHCAR2NAPRTTSHRSRD5A2 | |
| Hydrochloric Acid SCHEMBL7476482 | 0.79 | HCAR2 (0.48) | TTRHCAR2NAPRTTSHRMGAM | |
| SCHEMBL27751624 | 0.78 | KDM4E (0.50) | HCAR2NAPRTTSHRMGAMP4HA1 | |
| SCHEMBL8061081 | 0.78 | GABRP (0.47) | TTRHCAR2NAPRTTSHRMGAM | |
| SCHEMBL487373 | 0.78 | HCAR2 (0.47) | TTRHCAR2NAPRTTSHRSRD5A2 | |
| SCHEMBL1105964 | 0.78 | HCAR2 (0.47) | TTRHCAR2NAPRTTSHRSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 144 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5939568-A | Accelerated catalysis of olefinic epoxidations | THE SCRIPPS RESEARCH INSTITUTE (US) | 1999-08-17 | — | — | US | claimed |
| WO-1998033786-A9 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | — | 1998-12-30 | — | — | WO | claimed |
| WO-1998033786-A1 | ACCELERATED CATALYSIS OF OLEFINIC EPOXIDATIONS | THE SCRIPPS RESEARCH INSTITUTE (US) | 1998-08-06 | — | — | WO | claimed |
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | claimed |
| CN-119080739-B | Synthesis method of 5-chloro-6- (4- (ethoxycarbonyl) piperidin-1-yl) nicotinic acid | 深圳智微通科技有限公司 | 2025-02-25 | — | — | CN | disclosed |
| CN-119080739-A | Synthesis method of 5-chloro-6- (4- (ethoxycarbonyl) piperidin-1-yl) nicotinic acid | 深圳智微通科技有限公司 | 2024-12-06 | — | — | CN | disclosed |
| CN-116836157-A | Oxadiazole derivative and preparation method and application thereof | 星希尔生物科技(上海)有限公司 | 2023-10-03 | — | — | CN | disclosed |
| WO-2023179366-A1 | OXADIAZOLE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 星希尔生物科技(上海)有限公司 | 2023-09-28 | — | — | WO | disclosed |
| CN-109836379-B | Method for converting halogenated pyridine carboxylic acid into cyano-substituted pyridine carboxylic acid | 济南韶远医药技术有限公司 | 2022-10-21 | — | — | CN | disclosed |
| US-10875888-B2 | Steroid derivative FXR agonist | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2020-12-29 | — | — | US | disclosed |
| US-10442765-B2 | Method for producing 2,3-dichloro-5-(trichloromethyl)pyridine | CHEMINOVA A/S (DK) | 2019-10-15 | — | — | US | disclosed |
| US-20180057459-A1 | METHOD FOR PRODUCING 2,3-DICHLORO-5-(TRICHLOROMETHYL)PYRIDINE | CHEMINOVA A/S (DK) | 2018-03-01 | — | — | US | disclosed |
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |
| EP-0136593-A2 | Novel halopyridines and methods of making | THE DOW CHEMICAL COMPANY (US) | 1985-04-10 | — | — | EP | disclosed |
| EP-0046653-B1 | METHOD FOR CONVERTING CARBOXYLIC ACID GROUPS TO TRICHLOROMETHYL GROUPS | THE DOW CHEMICAL COMPANY (US) | 1984-05-16 | — | — | EP | disclosed |
| US-4419514-A | Method for converting carboxylic acid groups to trichloromethyl groups | THE DOW CHEMICAL COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| US-4410530-A | CARDIO-SELECTIVE B-RECEPTOR BLOCKING AGENTS AND STIMULANTS | CIBA-GEIGY CORPORATION (US) | 1983-10-18 | — | — | US | disclosed |
| EP-0046653-A1 | Method for converting carboxylic acid groups to trichloromethyl groups | THE DOW CHEMICAL COMPANY (US) | 1982-03-03 | — | — | EP | disclosed |
| US-4195090-A | ADRENERGIC BLOCKING AGENTS | CIBA-GEIGY CORPORATION (US) | 1980-03-25 | — | — | US | disclosed |
| US-4115575-A | CARDIOVASCULAR DISORDERS | CIBA-GEIGY CORPORATION (US) | 1978-09-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180057459-A1 | METHOD FOR PRODUCING 2,3-DICHLORO-5-(TRICHLOROMETHYL)PYRIDINE | CBR3, USP5, CDC5L | TTR 4298/4885HCAR2 3294/4885NAPRT 2939/4885 |
| US-10442765-B2 | Method for producing 2,3-dichloro-5-(trichloromethyl)pyridine | CBR3, USP5, CDC5L | TTR 4298/4885HCAR2 3294/4885NAPRT 2939/4885 |
| US-10875888-B2 | Steroid derivative FXR agonist | NR1H4, SLC10A1, FXR1 | TTR 967/4885HCAR2 422/4885NAPRT 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.