Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 19/20 | 0.50 |
| ▸ | F11 | P03951 | 12/20 | 0.50 |
| ▸ | TPSB2 | P20231 | 9/20 | 0.50 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.50 |
| ▸ | PLG | P00747 | 2/20 | 0.50 |
| ▸ | PLAU | P00749 | 2/20 | 0.50 |
| ▸ | F7 | P08709 | 2/20 | 0.50 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.42 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | F9 | P00740 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23219187 | 0.92 | CFD (0.62) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29852721 | 0.92 | CFD (0.62) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23229195 | 0.91 | CFD (0.42) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218961 | 0.85 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29852853 | 0.85 | CFD (0.49) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL29853183 | 0.82 | CFD (0.58) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218593 | 0.82 | CFD (0.58) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23229126 | 0.82 | CFD (0.55) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL28736236 | 0.81 | CFD (0.44) | CFDF11TPSB2KLKB1PLG | |
| SCHEMBL23218742 | 0.80 | CFD (0.65) | CFDF11TPSB2KLKB1PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021072198-A1 | ORAL COMPLEMENT FACTOR D INHIBITORS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2021-04-15 | — | — | WO | disclosed |