Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DEGS1 | O15121 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | WNT3A | P56704 | 5/20 | 0.42 |
| ▸ | FEN1 | P39748 | 5/20 | 0.42 |
| ▸ | ALOX5AP | P20292 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.40 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2418638 | 0.89 | DEGS1 (0.43) | DEGS1ABL1WNT3ANPY5RTBK1 | |
| SCHEMBL2319143 | 0.88 | NPY5R (0.47) | DEGS1ABL1WNT3AFEN1ALOX5AP | |
| SCHEMBL2319121 | 0.84 | NPY5R (0.48) | DEGS1ABL1WNT3ANPY5RTBK1 | |
| SCHEMBL2419345 | 0.81 | ABL1 (0.50) | DEGS1ABL1WNT3ANPY5RHDAC1 | |
| SCHEMBL2320672 | 0.78 | WNT3A (0.53) | DEGS1ABL1WNT3ANPY5RHDAC1 | |
| SCHEMBL2317319 | 0.78 | DEGS1 (0.45) | DEGS1WNT3ANPY5RTBK1HDAC1 | |
| SCHEMBL13362250 | 0.78 | NPY5R (0.46) | DEGS1WNT3ANPY5RTBK1HDAC1 | |
| SCHEMBL2321207 | 0.77 | USP30 (0.52) | DEGS1ABL1WNT3AFEN1ALOX5AP | |
| SCHEMBL2319777 | 0.77 | USP30 (0.47) | DEGS1NPY5RTBK1HDAC1HDAC2 | |
| SCHEMBL2320718 | 0.76 | DEGS1 (0.43) | DEGS1WNT3AHDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2011-09-22 | — | — | US | disclosed |
| EP-2352730-A2 | BIOLOGICALLY ACTIVE AMIDES | H. Lundbeck A/S (DK) | 2011-08-10 | — | — | EP | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
| WO-2010053861-A2 | BIOLOGICALLY ACTIVE AMIDES | H. LUNDBECK A/S (DK) | 2010-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110230497-A1 | BIOLOGICALLY ACTIVE AMIDES | NPY5R, NPY1R, NPY2R | DEGS1 3961/4885ABL1 985/4885WNT3A 4719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.