Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.34 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | RPLP1 | P05386 | 1/20 | 0.33 |
| ▸ | RPLP0 | P05388 | 1/20 | 0.33 |
| ▸ | RPS17 | P08708 | 1/20 | 0.33 |
| ▸ | RPSA | P08865 | 1/20 | 0.33 |
| ▸ | RPS2 | P15880 | 1/20 | 0.33 |
| ▸ | RPL35A | P18077 | 1/20 | 0.33 |
| ▸ | RPL7 | P18124 | 1/20 | 0.33 |
| ▸ | RPL17 | P18621 | 1/20 | 0.33 |
| ▸ | RPS4Y1 | P22090 | 1/20 | 0.33 |
| ▸ | RPS3 | P23396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL652758 | 0.92 | LMNA (0.70) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL650188 | 0.90 | LMNA (0.64) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL650199 | 0.90 | LMNA (0.64) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL650299 | 0.89 | LMNA (0.68) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL649986 | 0.89 | LMNA (0.68) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL10124495 | 0.89 | LMNA (0.57) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL652759 | 0.87 | LMNA (0.68) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL652760 | 0.87 | LMNA (0.68) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL648757 | 0.86 | LMNA (0.61) | CYP3A4LMNAMEN1KMT2ATSHR | |
| SCHEMBL648769 | 0.86 | LMNA (0.61) | CYP3A4LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1966129-B1 | CARBONATES OF FENICOL ANTIBIOTICS | SCHERING PLOUGH LTD (CH) | 2011-08-17 | — | — | EP | claimed |