SCHEMBL23239793

SCHEMBL23239793

CC(C)(C)OC(=O)NC1C([C@H](O)[C@H](O)CO)OC(C)(C)C[C@H]1O

nearest known ligand 0.41

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ NANP Q8TBE9 3/20 0.38
▸ MAG P20916 3/20 0.34
▸ SIGLEC7 Q9Y286 1/20 0.34
▸ SELL P14151 1/20 0.34
▸ SELP P16109 1/20 0.34
▸ NEU3 Q9UQ49 3/20 0.33
▸ NEU4 Q8WWR8 2/20 0.33
▸ NEU2 Q9Y3R4 2/20 0.33
▸ NEU1 Q99519 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20259100 0.83 NANP (0.52) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL31695272 0.80 NANP (0.39) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL29226083 0.77 NANP (0.54) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL31695253 0.76 CD22 (0.51) NANPMAGSIGLEC7
SCHEMBL31695064 0.76 NANP (0.38) NANPMAGSIGLEC7SELLSELP
SCHEMBL17215078 0.73 NEU3 (0.34) L3MBTL1NANPNEU3NEU4NEU2
SCHEMBL29226059 0.73 NANP (0.59) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL15491955 0.72 NANP (0.54) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL468825 0.72 NANP (0.54) L3MBTL1NANPMAGSIGLEC7SELL
SCHEMBL12257455 0.72 NANP (0.53) L3MBTL1NANPMAGSIGLEC7SELL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11639364-B2 Potent sialyltransferase inhibitors STICHTING RADBOUD UNIVERSITEIT (NL) 2023-05-02 — — US disclosed
US-20210107931-A1 New potent sialyltransferase inhibitors STICHTING KATHOLIEKE UNIVERSITEIT (NL) 2021-04-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210107931-A1 New potent sialyltransferase inhibitors NMT1, NEU1, NMT2 L3MBTL1 1290/4885NANP 26/4885MAG 160/4885
US-11639364-B2 Potent sialyltransferase inhibitors NEU1, NMT1, NEU2 L3MBTL1 1547/4885NANP 25/4885MAG 174/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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