Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15211469 | 0.75 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL11922107 | 0.74 | KDM4E (0.32) | KDM4E | |
| SCHEMBL26937725 | 0.74 | KDM4E (0.30) | KDM4E | |
| SCHEMBL24126818 | 0.73 | — | — | |
| SCHEMBL19745527 | 0.72 | ALDH1A1 (0.39) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL23890468 | 0.71 | KDM4E (0.31) | KDM4E | |
| SCHEMBL23240261 | 0.71 | — | — | |
| SCHEMBL15181429 | 0.69 | KDM4E (0.37) | KDM4EHSD17B10 | |
| SCHEMBL5576637 | 0.68 | MEN1 (0.40) | KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26569667 | 0.67 | KDM4E (0.31) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021070132-A1 | BI-ARYL DIHYDROOROTATE DEHYDROGENASE INHIBITORS | JANSSEN BIOTECH, INC. (US) | 2021-04-15 | — | — | WO | disclosed |