Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ACACB | O00763 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6444899 | 0.85 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL69791 | 0.81 | HTT (0.69) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL21981938 | 0.79 | HTT (0.67) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL28422449 | 0.79 | ALDH1A1 (0.63) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL19736947 | 0.78 | ALDH1A1 (0.61) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| Ethylene SCHEMBL22615238 | 0.77 | HTT (0.64) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL19442049 | 0.76 | HTT (0.58) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| Propane SCHEMBL28412029 | 0.75 | HTT (0.68) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL25826853 | 0.74 | HTT (0.61) | ALDH1A1LMNAKDM4EL3MBTL1HTT | |
| SCHEMBL15268180 | 0.74 | HTT (0.60) | ALDH1A1LMNAKDM4EL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |