SCHEMBL23246764

SCHEMBL23246764

COc1ccc2nc(-c3ccc(N4CCC(O)(CO)CC4)nc3)sc2c1

nearest known ligand 0.53

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
APP P05067 12/20 0.53
WNT3A P56704 1/20 0.47
SNCA P37840 1/20 0.46
GLA P06280 1/20 0.46
GAA P10253 1/20 0.46
SULT1A1 P50225 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29764555 1.00 APP (0.53) APPWNT3ASNCAGLAGAA
SCHEMBL2055250 0.85 APP (0.71) APPSNCAGLAGAASULT1A1
SCHEMBL23263904 0.84 APP (0.53) APPWNT3AGLAGAASULT1A1
SCHEMBL2055194 0.83 APP (0.59) APPSNCAGLAGAA
SCHEMBL23327788 0.82 APP (0.52) APPWNT3AGLAGAASULT1A1
SCHEMBL2055187 0.82 APP (0.58) APPSNCAGLAGAA
SCHEMBL2055226 0.82 APP (0.74) APPWNT3ASNCAGLAGAA
SCHEMBL21469221 0.81 APP (0.50) APPWNT3AGLAGAA
SCHEMBL5117916 0.81 APP (0.56) APPSNCAGLAGAASULT1A1
SCHEMBL23246219 0.80 APP (0.51) APPWNT3AGLAGAASULT1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240165276-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES CBD SOLUTIONS AB (SE) 2024-05-23 US claimed
EP-4045495-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES Karin & Sten Mortstedt CBD Solutions AB (SE) 2022-08-24 EP claimed
WO-2021074351-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) 2021-04-22 WO claimed
US-20240165276-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES CBD SOLUTIONS AB (SE) 2024-05-23 US disclosed
EP-4045495-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES Karin & Sten Mortstedt CBD Solutions AB (SE) 2022-08-24 EP disclosed
WO-2021074351-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) 2021-04-22 WO disclosed
WO-2021074351-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES KARIN & STEN MORTSTEDT CBD SOLUTIONS AB (SE) 2021-04-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240165276-A1 SELECTIVE LIGANDS FOR TAU AGGREGATES MAPT, FUS, PSEN1 APP 4/4885WNT3A 4173/4885SNCA 48/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.