Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SNCA | P37840 | 1/20 | 0.47 |
| ▸ | SULT1A1 | P50225 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2055194 | 0.89 | APP (0.59) | APPGLAGAASNCA | |
| SCHEMBL2055250 | 0.88 | APP (0.71) | APPGLAGAASNCASULT1A1 | |
| SCHEMBL2055187 | 0.85 | APP (0.58) | APPGLAGAASNCA | |
| SCHEMBL2055226 | 0.85 | APP (0.74) | APPGLAGAASNCA | |
| SCHEMBL2055258 | 0.84 | APP (0.50) | APP | |
| SCHEMBL23327788 | 0.82 | APP (0.52) | APPGLAGAASULT1A1 | |
| SCHEMBL21462494 | 0.82 | APP (0.52) | APPGLAGAA | |
| SCHEMBL23263904 | 0.81 | APP (0.53) | APPGLAGAASULT1A1 | |
| SCHEMBL23246764 | 0.81 | APP (0.53) | APPGLAGAASNCASULT1A1 | |
| SCHEMBL29764555 | 0.81 | APP (0.53) | APPGLAGAASNCASULT1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1981883-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | AstraZeneca AB (SE) | 2008-10-22 | — | — | EP | disclosed |
| WO-2007086800-A1 | NOVEL HETEROARYL SUBSTITUTED BENZOTHIAZOLES | ASTRAZENECA AB (SE) | 2007-08-02 | — | — | WO | disclosed |