SCHEMBL23247265

SCHEMBL23247265

Cc1ccc2nc(-c3ccc4cc(C)ccc4n3)ccc2c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 4/20 0.68
NCK1 P16333 1/20 0.63
BACE1 P56817 1/20 0.63
CYP2A6 P11509 3/20 0.55
ALDH1A1 P00352 5/20 0.52
NQO2 P16083 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
KMT2A Q03164 2/20 0.44
MEN1 O00255 1/20 0.44
PSMB5 P28074 1/20 0.44
ESR1 P03372 1/20 0.44
ESR2 Q92731 1/20 0.44
KDM4E B2RXH2 3/20 0.42
NPC1 O15118 1/20 0.42
HPGD P15428 1/20 0.42
NFKB1 P19838 1/20 0.42
RAB9A P51151 1/20 0.42
NFKB2 Q00653 1/20 0.42
RELA Q04206 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15831562 0.88 CYP1A2 (0.55) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL15831553 0.88 CCR1 (0.59) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL10147842 0.87 CYP1A2 (0.59) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL15831559 0.87 CYP1A2 (0.58) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL15824289 0.87 CYP1A2 (0.63) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL14269734 0.87 CCR1 (0.61) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL4128022 0.86 CYP1A2 (0.57) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL13298969 0.84 CYP1A2 (0.55) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL29692924 0.84 PSMB5 (0.57) CYP1A2NCK1BACE1CYP2A6ALDH1A1
SCHEMBL8830006 0.84 PSMB5 (0.57) CYP1A2NCK1BACE1CYP2A6ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021074275-A1 EFFECTIVE PHOTOMODULATION OF LANTHANIDE (III) ION LUMINESCENCE IN THE VISIBLE OR NEAR-INFRARED RANGE UNIVERSITE DE RENNES 1 (FR) 2021-04-22 WO disclosed
CN-105294776-B A kind of preparation method of the symmetrical dimer of nitrogen heterocyclic ring aromatic compound 兰州大学 2018-06-15 CN disclosed
CN-105294776-A Method for preparing symmetric dimer of nitrogen heterocyclic ring aromatic compound UNIV LANZHOU 2016-02-03 CN disclosed