Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | NCK1 | P16333 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29692924 | 1.00 | PSMB5 (0.57) | PSMB5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL10147842 | 0.89 | CYP1A2 (0.59) | PSMB5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL3296780 | 0.87 | CYP1A2 (0.53) | PSMB5CYP1A2ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL398766 | 0.87 | KDM4E (0.55) | PSMB5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL23247265 | 0.84 | CYP1A2 (0.68) | PSMB5CYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL14508588 | 0.84 | PSMB5 (0.44) | PSMB5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL19037226 | 0.83 | PSMB5 (0.46) | PSMB5CYP1A2ALDH1A1KDM4EMAPT | |
| SCHEMBL4128022 | 0.83 | CYP1A2 (0.57) | PSMB5CYP1A2ALDH1A1KDM4EMEN1 | |
| SCHEMBL14759469 | 0.82 | NPC1 (0.59) | CYP1A2ALDH1A1KDM4EMAPTMEN1 | |
| SCHEMBL11811065 | 0.82 | CYP1A2 (0.52) | CYP1A2ALDH1A1KDM4EMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111471009-A | Preparation method and application of 2-arylquinoline derivative | 安阳师范学院 | 2020-07-31 | — | — | CN | claimed |
| CN-117229204-A | Method for preparing quinoline derivative by catalytic conversion of lignin by rhodium-based catalyst | 中国科学院大连化学物理研究所 | 2023-12-15 | — | — | CN | disclosed |
| CN-112587713-B | Novel sanitary towel with antibacterial function and production process thereof | 周旭龙 | 2022-09-13 | — | — | CN | disclosed |
| CN-112587713-A | Novel sanitary towel with antibacterial function and production process thereof | 周旭龙 | 2021-04-02 | — | — | CN | disclosed |
| US-10957869-B2 | Organic luminescent materials containing cycloalkyl ancillary ligands | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2021-03-23 | — | — | US | disclosed |
| CN-111471009-A | Preparation method and application of 2-arylquinoline derivative | 安阳师范学院 | 2020-07-31 | — | — | CN | disclosed |
| CN-107400084-B | Method for synthesizing quinoline derivative | 南京理工大学 | 2020-04-10 | — | — | CN | disclosed |
| US-20190103574-A1 | ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2019-04-04 | — | — | US | disclosed |
| US-20190077818-A1 | ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS | Beijing Summer Sprout Technology Co., Ltd. (CN) | 2019-03-14 | — | — | US | disclosed |
| CN-107400084-A | A kind of method of synthesis of quinoline derivatives | 南京理工大学 | 2017-11-28 | — | — | CN | disclosed |
| US-5670526-A | ANTIINFLAMMATORY AGENT, IMMUNOSUPPRESSANT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| US-5627193-A | MEDICAL DIAGNOSIS, CARDIOVASCULAR DIAORDERS AND PROTECTION OF ORGANS FOR TRANSPLANTATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1997-05-06 | — | — | US | disclosed |
| EP-0452712-B1 | 4-Quinolyl-dihydropyridines, process for their prepatation and their use in medicaments | BAYER AG (DE) | 1995-04-19 | — | — | EP | disclosed |
| EP-0452712-A1 | 4-Quinolyl-dihydropyridines, process for their prepatation and their use in medicaments | BAYER AG (DE) | 1991-10-23 | — | — | EP | disclosed |
| US-3973022-A | Quinolineacetic acid compositions | CIBA-GEIGY CORPORATION (US) | 1976-08-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190103574-A1 | ORGANIC LUMINESCENT MATERIALS CONTAINING CYCLOALKYL ANCILLARY LIGANDS | ACAT1, ACACA, ACAT2 | PSMB5 4813/4885CYP1A2 857/4885ALDH1A1 42/4885 |
| US-10957869-B2 | Organic luminescent materials containing cycloalkyl ancillary ligands | ACAT1, ACACA, ACAT2 | PSMB5 4813/4885CYP1A2 857/4885ALDH1A1 42/4885 |
| US-20190077818-A1 | ORGANIC LUMINESCENT MATERIALS CONTAINING FLUORINE ANCILLARY LIGANDS | FOXO1, NAA15, FOXK1 | PSMB5 4831/4885CYP1A2 422/4885ALDH1A1 16/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.