Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.66 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26989010 | 0.88 | PRCP (0.70) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247921 | 0.86 | PRCP (0.67) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247284 | 0.83 | CYP3A4 (0.55) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247560 | 0.82 | PRCP (0.64) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL31165616 | 0.82 | PRCP (0.62) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL29666088 | 0.81 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247438 | 0.81 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL27003154 | 0.81 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247554 | 0.80 | CYP3A4 (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247532 | 0.79 | PRCP (0.58) | PRCPOPRM1OPRD1HCRTR1HCRTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4045491-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | Givaudan SA (CH) | 2022-08-24 | — | — | EP | claimed |
| WO-2021074281-A1 | SUBSTITUTED AZACYLES AS TRMP8 MODULATORS | GIVAUDAN SA (CH) | 2021-04-22 | — | — | WO | claimed |