Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 10/20 | 0.70 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.51 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.51 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.50 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23247921 | 0.92 | PRCP (0.67) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247282 | 0.88 | PRCP (0.66) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL27003154 | 0.88 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL26987059 | 0.88 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247560 | 0.86 | PRCP (0.64) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL31165616 | 0.86 | PRCP (0.62) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247438 | 0.85 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL29666088 | 0.85 | PRCP (0.61) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL23247532 | 0.84 | PRCP (0.58) | PRCPOPRM1OPRD1HCRTR1HCRTR2 | |
| SCHEMBL19323955 | 0.84 | PRCP (0.52) | PRCPOPRM1OPRD1CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024011086-A1 | COMPOSITIONS THAT ENHANCE THE COOLING EFFECT | FIRMENICH INCORPORATED (US) | 2024-01-11 | — | — | WO | claimed |
| EP-4192422-A1 | COOLING SENSATION COMPOSITIONS | Givaudan SA (CH) | 2023-06-14 | — | — | EP | disclosed |
| WO-2022028726-A1 | COOLING SENSATION COMPOSITIONS | GIVAUDAN SA (CH) | 2022-02-10 | — | — | WO | disclosed |