Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 11/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 11/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.34 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.32 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3214568 | 0.83 | PDGFRB (0.52) | PDGFRBPDGFRA | |
| SCHEMBL3231976 | 0.79 | PDGFRB (0.36) | PDGFRBPDGFRA | |
| SCHEMBL3222965 | 0.79 | PDGFRB (0.34) | PDGFRBPDGFRA | |
| SCHEMBL23247558 | 0.78 | PDGFRB (0.37) | PDGFRBPDGFRATLR8KCNQ3KCNQ2 | |
| SCHEMBL13495737 | 0.78 | PDGFRB (0.36) | PDGFRBPDGFRA | |
| SCHEMBL18318550 | 0.76 | PDGFRB (0.52) | PDGFRBPDGFRA | |
| SCHEMBL31475475 | 0.76 | PDGFRB (0.46) | PDGFRBPDGFRA | |
| SCHEMBL24096780 | 0.76 | PDGFRB (0.46) | PDGFRBPDGFRA | |
| SCHEMBL3217596 | 0.76 | PDGFRB (0.34) | PDGFRBPDGFRA | |
| SCHEMBL3234849 | 0.76 | PDGFRB (0.37) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021074279-A1 | SPIRO-FUSED TRICYCLIC MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-22 | — | — | WO | disclosed |
| WO-2021074279-A1 | SPIRO-FUSED TRICYCLIC MAP4K1 INHIBITORS | BAYER AKTIENGESELLSCHAFT (DE) | 2021-04-22 | — | — | WO | disclosed |