SCHEMBL3214568

SCHEMBL3214568

COc1cc2cc(Br)cnc2cc1F

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDGFRB P09619 19/20 0.52
PDGFRA P16234 19/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18318550 0.93 PDGFRB (0.52) PDGFRBPDGFRA
SCHEMBL8501715 0.86 PDGFRB (0.56) PDGFRBPDGFRA
SCHEMBL3877724 0.83 PDGFRB (0.55) PDGFRBPDGFRA
SCHEMBL23247348 0.83 PDGFRB (0.40) PDGFRBPDGFRA
SCHEMBL620753 0.80 PDGFRB (0.52) PDGFRBPDGFRA
SCHEMBL3214752 0.80 PDGFRB (0.49) PDGFRBPDGFRA
SCHEMBL622733 0.80 PDGFRB (0.52) PDGFRBPDGFRA
SCHEMBL16537787 0.80 PDGFRB (0.48) PDGFRBPDGFRA
SCHEMBL31475475 0.80 PDGFRB (0.46) PDGFRBPDGFRA
SCHEMBL24096780 0.80 PDGFRB (0.46) PDGFRBPDGFRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100056570-A1 FUNGICIDES SYNGENTA CROP PROTECTION, INC. (US) 2010-03-04 US disclosed
WO-2010015680-A1 FUNGICIDE OXYALKYLAMIDE DERIVATIVES BAYER CROPSCIENCE SA (FR) 2010-02-11 WO disclosed
EP-2068632-A1 FUNGICIDES Syngeta Participations AG (CH) 2009-06-17 EP disclosed
WO-2008028624-A1 FUNGICIDES SYNGENTA PARTICIPATIONS AG (CH) 2008-03-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056570-A1 FUNGICIDES CYP21A2, CYP51A1, CYP4X1 PDGFRB 4516/4885PDGFRA 4427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.