SCHEMBL232483

SCHEMBL232483

NOP(=O)(O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.54
CA4 P22748 2/20 0.54
CA5A P35218 2/20 0.54
CA12 O43570 1/20 0.49
CA1 P00915 1/20 0.49
CA7 P43166 1/20 0.49
CA9 Q16790 1/20 0.49
CA5B Q9Y2D0 1/20 0.49
CFTR P13569 1/20 0.48
TSHR P16473 2/20 0.45
ALOX15 P16050 1/20 0.45
USP2 O75604 1/20 0.45
ALDH1A1 P00352 3/20 0.43
L3MBTL1 Q9Y468 2/20 0.43
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43
SRC P12931 1/20 0.43
POLB P06746 1/20 0.42
TDP1 Q9NUW8 1/20 0.41
GAA P10253 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7128526 0.80 CA2 (0.59) CA2CA4CA5ACA12CA1
SCHEMBL11583769 0.78 CA2 (0.56) CA2CA4CA5ACA12CA1
SCHEMBL15864290 0.77 CA2 (0.50) CA2CA4CA5ACA12CA1
SCHEMBL4433566 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL7872619 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL344018 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL9309606 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL28247571 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL26922020 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1
SCHEMBL177263 0.76 CA2 (0.54) CA2CA4CA5ACA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 305 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111662328-B Derivative of flame-retardant environment-friendly toluene diisocyanate and synthetic method thereof 万华节能科技集团股份有限公司 2021-10-15 CN claimed
CN-111592568-B Derivative of flame-retardant environment-friendly diphenylmethane diisocyanate and synthetic method thereof 万华节能科技集团股份有限公司 2021-09-28 CN claimed
CN-107592895-B Method of pumping an aqueous fluid containing a surface modifying treatment agent into a well 通用电气(GE)贝克休斯有限责任公司 2020-12-25 CN claimed
EP-3268447-B1 METHOD OF PUMPING AQUEOUS FLUID CONTAINING SURFACE MODIFYING TREATMENT AGENT INTO A WELL BAKER HUGHES HOLDINGS LLC (US) 2020-12-16 EP claimed
CN-111662328-A Derivative of flame-retardant environment-friendly toluene diisocyanate and synthetic method thereof 万华节能科技集团股份有限公司 2020-09-15 CN claimed
CN-111592568-A Derivative of flame-retardant environment-friendly diphenylmethane diisocyanate and synthetic method thereof 万华节能科技集团股份有限公司 2020-08-28 CN claimed
CN-111498866-A Organic hybrid-C L O structure silicoaluminophosphate molecular sieve and preparation method thereof 北京化工大学 2020-08-07 CN claimed
US-10704365-B2 Method of inhibiting deposition of contaminants onto a metallic surface with a surface modifying treatment agent BAKER HUGHES, A GE COMPANY, LLC (US) 2020-07-07 US claimed
CN-111333083-A Organic hybrid-CLO structure aluminum phosphate molecular sieve and preparation method thereof 北京化工大学 2020-06-26 CN claimed
US-10648304-B2 Method of using surface modifying treatment agents to treat subterranean formations BAKER HUGHES, A GE COMPANY, LLC (US) 2020-05-12 US claimed
US-20150083416-A1 METHOD OF USING SURFACE MODIFYING TREATMENT AGENTS TO TREAT SUBTERRANEAN FORMATIONS BAKER HUGHES HOLDINGS LLC 2015-03-26 US claimed
US-20150083397-A1 METHOD OF INHIBITING FOULING ON A METALLIC SURFACE USING A SURFACE MODIFYING TREATMENT AGENT BAKER HUGHES HOLDINGS LLC 2015-03-26 US claimed
CN-102145885-A Method for preparing surface phosphorylated water-soluble carbon nanotube and prepared carbon nanotube UNIV NANJING NORMAL 2011-08-10 CN claimed
EP-1196158-A4 CURCUMIN AND CURCUMINOID INHIBITION OF ANGIOGENESIS UNIV EMORY (US) 2004-05-26 EP claimed
US-6555175-B2 Process for the surface modification of a polymeric substrate Johnson, Joseph E. 2003-04-29 US claimed
US-20020197467-A1 Process for the surface modification of a polymeric substrate PROTEUS CORPORATION 2002-12-26 US claimed
EP-1196158-A1 CURCUMIN AND CURCUMINOID INHIBITION OF ANGIOGENESIS EMORY UNIVERSITY (US) 2002-04-17 EP claimed
US-20020006966-A1 CURCUMIN AND CURCUMINOID INHIBITION OF ANGIOGENESIS NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2002-01-17 US claimed
US-20010025034-A1 Curcumin and curcuminoid inhibition of angiogenesis EMORY UNIVERSITY 2001-09-27 US claimed
WO-2001000201-A1 CURCUMIN AND CURCUMINOID INHIBITION OF ANGIOGENESIS EMORY UNIVERSITY (US) 2001-01-04 WO claimed