SCHEMBL23248802

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL23199759	0.90	JAK2 (0.33)	ALDH1A1JAK2BTKLPLLIPG
	SCHEMBL24109664	0.88	CYP3A4 (0.41)	ALDH1A1JAK2BTKCYP3A4TSHR
	SCHEMBL20540203	0.86	LPL (0.39)	JAK2BTKLPLLIPG
	SCHEMBL1494643	0.83	LPL (0.37)	ALDH1A1JAK2BTKCYP3A4TSHR
	SCHEMBL29503402	0.81	CYP3A4 (0.46)	ALDH1A1JAK2BTKCYP3A4TSHR
	SCHEMBL106726	0.81	CYP3A4 (0.46)	ALDH1A1JAK2BTKCYP3A4TSHR
	SCHEMBL23202718	0.81	KDM1A (0.31)	ALDH1A1
	SCHEMBL29993417	0.79	JAK2 (0.39)	ALDH1A1JAK2BTKHPGDSMN1; SMN2
	SCHEMBL20540300	0.78	JAK2 (0.41)	JAK2BTKLPLLIPG
	SCHEMBL29724522	0.78	JAK2 (0.41)	JAK2BTKLPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.