Sulfurous Acid

Sulfurous Acid

SCHEMBL23249641

I.O.O.O.O.O.O.O.O=S(O)O.[NaH].[NaH]

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG

The experimentally established mechanism targets of Sulfurous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.67
CA2 P00918 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfurous Acid SCHEMBL1093823 0.94 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL27391564 0.94
Sulfurous Acid SCHEMBL3884261 0.94 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL9117249 0.94 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL3771285 0.94 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL8003764 0.94
Sulfurous Acid SCHEMBL28048784 0.94 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL3186682 0.94
Sulfurous Acid SCHEMBL9436266 0.94
Sulfurous Acid SCHEMBL23249640 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4043451-B1 METHODS FOR THE PREPARATION OF AN INTERMEDIATE IN THE SYNTHESIS OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORP (US) 2024-02-28 EP disclosed
EP-4284793-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC Corporation (US) 2023-12-06 EP disclosed
EP-4284794-A1 METHOD FOR PREPARING TERT-BUTYL N-((1R,2S,5S)-2-((2-((5-CHLOROPYRIDIN-2-YL)AMINO)-2-OXOACETYL)AMINO)-5-(DIMETHYLCARBAMOYL)CYCLOHEXYL)CARBAMATE FMC Corporation (US) 2023-12-06 EP disclosed
EP-4253380-A2 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC Corporation (US) 2023-10-04 EP disclosed
CN-116724032-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2023-09-08 CN disclosed
CN-116724033-A Method for preparing tert-butyl N- ((1R, 2S, 5S) -2- ((2- ((5-chloropyridin-2-yl) amino) -2-oxoacetyl) amino) -5- (dimethylcarbamoyl) cyclohexyl) carbamate FMC公司 2023-09-08 CN disclosed
EP-4219455-A1 METHODS FOR THE PREPARATION OF A HALOGENATED PYRAZOLE FMC Corporation (US) 2023-08-02 EP disclosed
EP-3976591-B1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORP (US) 2023-04-19 EP disclosed
EP-3976589-B1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORP (US) 2023-04-12 EP disclosed
CN-114650987-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-21 CN disclosed
CN-114650984-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-21 CN disclosed
CN-114641471-A Process for the preparation of 5-bromo-2- (3-chloro-pyridin-2-yl) -2H-pyrazole-3-carboxylic acid FMC公司 2022-06-17 CN disclosed
WO-2021076832-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2021-04-22 WO disclosed
WO-2021076835-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2021-04-22 WO disclosed
WO-2021076839-A1 METHODS FOR THE PREPARATION OF 5-BROMO-2-(3-CHLORO-PYRIDIN-2-YL)-2H-PYRAZOLE-3-CARBOXYLIC ACID FMC CORPORATION (US) 2021-04-22 WO disclosed