Sulfurous Acid

Sulfurous Acid

SCHEMBL9117249

O.O.O.O.O.O.O.O.O.O=S(O)O.[NaH]

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Sulfurous Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.75
CA2 P00918 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Sulfurous Acid SCHEMBL9436266 1.00
Sulfurous Acid SCHEMBL27391564 1.00
Sulfurous Acid SCHEMBL1093823 1.00 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL3884261 1.00 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL3186682 1.00
Sulfurous Acid SCHEMBL3771285 1.00 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL8003764 1.00
Sulfurous Acid SCHEMBL28048784 1.00 CA1 (0.75) CA1CA2
Sulfurous Acid SCHEMBL23249641 0.94 CA1 (0.67) CA1CA2
Sulfurous Acid SCHEMBL28396462 0.94 CA1 (0.67) CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 76 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11926545-B2 Catalytic hydrogel membrane reactor for treatment of aqueous contaminants UNIVERSITY OF NOTRE DAME DU LAC (US) 2024-03-12 US disclosed
US-20210230028-A1 CATALYTIC HYDROGEL MEMBRANE REACTOR FOR TREATMENT OF AQUEOUS CONTAMINANTS UNIV NOTRE DAME DU LAC (US) 2021-07-29 US disclosed
US-9708340-B2 Urea derivatives and their use as fatty-acid binding protein (FABP) inhibitors HOFFMANN-LA ROCHE INC. (US) 2017-07-18 US disclosed
US-20160185795-A1 UREA DERIVATIVES AND THEIR USE AS FATTY-ACID BINDING PROTEIN (FABP) INHIBITORS HOFFMANN-LA ROCHE INC. (US) 2016-06-30 US disclosed
CN-103080240-B Solid solution pigment nanoparticles and method for producing solid solution pigment nanoparticles with controlled solid solution ratio M. TECHNIQUE Co.,Ltd. (JP) 2016-04-13 CN disclosed
CN-103145730-B Two thieno-fluorenes and derivative and preparation method EAST CHINA NORMAL UNIVERSITY (CN) 2016-02-03 CN disclosed
CN-105246876-A Condensed heterocyclic compound and pest control use thereof SUMITOMO CHEMICAL CO 2016-01-13 CN disclosed
CN-105143229-A Substituted xanthines and methods of use thereof HYDRA BIOSCIENCES INC 2015-12-09 CN disclosed
CN-104968663-A Fused heterocyclic compound SUMITOMO CHEMICAL CO 2015-10-07 CN disclosed
CN-102666548-B Tricyclic antibiotics BASILEA PHARMACEUTICA AG 2015-07-15 CN disclosed
CN-1220266-A Intermediates of protein kinase C inhibitors and preparation process thereof LILLY CO ELI (US) 1999-06-23 CN disclosed
CN-1035876-C Tetrahydrothiophene derivatives SANTEN PHARMACEUTICAL CO LTD (JP) 1997-09-17 CN disclosed
CN-1137794-A 5-(2-imidazolinylamino) benzimidazole derivatives, their preparation and their use as alpha-2 adrenoceptor agonists PROCTER & GAMBLE (US) 1996-12-11 CN disclosed
CN-1111247-A Protein kinase C inhibitors LILLY CO ELI (US) 1995-11-08 CN disclosed
WO-1995019185-A1 FUNCTIONALIZED AZA-MACROBICYCLIC LIGANDS FOR IMAGING APPLICATIONS MALLINCKRODT MEDICAL, INC. (US) 1995-07-20 WO disclosed
CN-1087338-A Therapeutical agent BOOTS CO PLC (GB) 1994-06-01 CN disclosed
US-5294375-A Thermochromic materials POLAROID CORPORATION (US) 1994-03-15 US disclosed
CN-1079739-A Tetrahydrothiophene derivatives SANTEN PHARMACEUTICAL CO LTD (JP) 1993-12-22 CN disclosed
CN-1022691-C Composition of free redical polymerization SHOWA DENKO KK (JP) 1993-11-10 CN disclosed
CN-1047515-A The composition of free redical polymerization SHOWA DENKO KK (JP) 1990-12-05 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160185795-A1 UREA DERIVATIVES AND THEIR USE AS FATTY-ACID BINDING PROTEIN (FABP) INHIBITORS FABP1, FABP5, FABP2 CA1 4491/4885CA2 3691/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.