SCHEMBL2325458

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2323346	0.89	FEN1 (0.47)	FEN1METPDK2TGFBR1
	SCHEMBL320352	0.82	FEN1 (0.49)	FEN1METPDK2RORCTGFBR1
	SCHEMBL2327513	0.81	MET (0.42)	FEN1METPDK2PDE3BPDE3A
	SCHEMBL19791355	0.79	MET (0.42)	FEN1METPDK2TGFBR1
	SCHEMBL2328404	0.79	MET (0.42)	MET
	SCHEMBL2325237	0.79	EGFR (0.43)	MET
	SCHEMBL12526278	0.78	FEN1 (0.46)	FEN1METPDK2TGFBR1
	SCHEMBL2325268	0.78	PDK2 (0.42)	FEN1METPDK2TGFBR1
	SCHEMBL12440215	0.78	FEN1 (0.39)	FEN1METPDK2TGFBR1
	SCHEMBL2364006	0.78	FEN1 (0.36)	FEN1METPDK2TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.