⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29890048 | 1.00 | — | — | |
| SCHEMBL4827728 | 0.81 | ESR2 (0.59) | — | |
| SCHEMBL150261 | 0.79 | — | — | |
| SCHEMBL23467002 | 0.77 | TSHR (0.38) | — | |
| SCHEMBL10876069 | 0.77 | SOS1 (0.58) | — | |
| SCHEMBL29617579 | 0.75 | — | — | |
| SCHEMBL224868 | 0.75 | — | — | |
| SCHEMBL29374280 | 0.75 | — | — | |
| 2,4-Dichlorofluorobenzene SCHEMBL530773 | 0.75 | — | — | |
| SCHEMBL15677 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1214 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109134204-B | Synthesis method of intermediate 2-bromo-4-fluoro-5-chlorophenol | 棓诺(苏州)新材料有限公司 | 2022-03-08 | — | — | CN | claimed |
| CN-113292494-A | Isoquinoline carboxylic acid compound and preparation method and application thereof | 江苏苏中药业集团股份有限公司 | 2021-08-24 | — | — | CN | claimed |
| US-10646482-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2020-05-12 | — | — | US | claimed |
| US-20190240213-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2019-08-08 | — | — | US | claimed |
| CN-109134204-A | The synthetic method of the fluoro- 5- chlorophenol of the bromo- 4- of intermediate 2- | 白银棓诺新材料有限公司 | 2019-01-04 | — | — | CN | claimed |
| US-10092558-B2 | Nitrogen-containing heteroaryl compounds and methods of use thereof | FIBROGEN, INC. (US) | 2018-10-09 | — | — | US | claimed |
| US-10035033-B2 | Fire extinguishing composition comprising alcohol phenol compound and derivative thereof | XI'AN WESTPEACE FIRE TECHNOLOGY CO., LTD. (CN) | 2018-07-31 | — | — | US | claimed |
| US-20170035747-A1 | NOVEL NITROGEN-CONTAINING HETEROARYL COMPOUNDS AND METHODS OF USE THEREOF | FIBROGEN, INC. | 2017-02-09 | — | — | US | claimed |
| EP-3095487-A1 | FIRE EXTINGUISHING COMPOSITION COMPRISING ALDOKETONES COMPOUND | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| EP-3095486-A2 | FIRE EXTINGUISHING COMPOSITION COMPRISING ALCOHOL PHENOL COMPOUND AND DERIVATIVE THEREOF | Xi'an J&R Fire Fighting Equipment Co., Ltd. (CN) | 2016-11-23 | — | — | EP | claimed |
| WO-2000050396-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 2000-08-31 | — | — | WO | claimed |
| WO-2000018724-A1 | (R)-CHIRAL HALOGENATED 1-SUBSTITUTEDAMINO-(n+1)-ALKANOLS USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-2000018723-A1 | SUBSTITUTED N-ALIPHATIC-N-AROMATIC TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-2000018721-A1 | SUBSTITUTED POLYCYCLIC ARYL AND HETEROARYL TERTIARY-HETEROALKYLAMINES USEFUL FOR INHIBITING CHOLESTERYL ESTER TRANSFER PROTEIN ACTIVITY | MONSANTO COMPANY (US) | 2000-04-06 | — | — | WO | claimed |
| WO-1999025687-A1 | AROMATIC SULFONE HYDROXAMIC ACID METALLOPROTEASE INHIBITOR | G.D. SEARLE & CO. (US) | 1999-05-27 | — | — | WO | claimed |
| US-5385990-A | Blend of epoxy compound, amine hardener and hydroxy substituted aromatic compound | LORD CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| EP-0596622-A2 | Epoxy resin structural adhesive composition having high temperature resistance | LORD CORPORATION (US) | 1994-05-11 | — | — | EP | claimed |
| EP-0188194-B1 | AMINOACRYLIC ACID DERIVATIVES | BAYER AG (DE) | 1990-07-04 | — | — | EP | claimed |
| EP-0188194-A2 | Aminoacrylic acid derivatives | BAYER AG (DE) | 1986-07-23 | — | — | EP | claimed |
| CN-86100221-A | AMINOACRYLIC ACID DERIVATIVES | — | 1986-07-16 | — | — | CN | claimed |