Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.34 |
| ▸ | PPARA | Q07869 | 2/20 | 0.34 |
| ▸ | CHUK | O15111 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | METAP2 | P50579 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.32 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23255438 | 1.00 | KIF11 (0.39) | KIF11CYP19A1CDK4CDK6PPARG | |
| SCHEMBL23255425 | 0.93 | KIF11 (0.37) | KIF11CYP19A1CDK4CDK6PPARG | |
| SCHEMBL23255428 | 0.93 | KIF11 (0.37) | KIF11CYP19A1CDK4CDK6PPARG | |
| SCHEMBL23255430 | 0.93 | KIF11 (0.42) | KIF11CYP19A1CHUKPDE10ACYP1A2 | |
| SCHEMBL23255581 | 0.92 | KIF11 (0.38) | KIF11CYP19A1CDK4CDK6PPARG | |
| SCHEMBL23255579 | 0.92 | KIF11 (0.38) | KIF11CYP19A1CDK4CDK6PPARG | |
| SCHEMBL18374580 | 0.89 | KIF11 (0.47) | KIF11PPARGPPARACYP1A2HSP90AA1 | |
| SCHEMBL23255679 | 0.89 | KIF11 (0.41) | KIF11CYP19A1PPARGPPARACHUK | |
| SCHEMBL17952924 | 0.88 | KDM4E (0.41) | CYP1A2METAP2KDM4EATML3MBTL1 | |
| SCHEMBL17952923 | 0.88 | KDM4E (0.41) | CYP1A2METAP2KDM4EATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3581570-B1 | CARBAZOLE-PYRIDINE-TRIFLUOROMETHYLPHENYL DERIVATIVES AND RELATED COMPOUNDS FOR USE AS TADF LUMINESCENT EMITTERS IN OLEDS | CYNORA GMBH (DE) | 2021-04-21 | — | — | EP | disclosed |