Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 4/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.41 |
| ▸ | NPY4R | P50391 | 4/20 | 0.38 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.38 |
| ▸ | NPY1R | P25929 | 3/20 | 0.38 |
| ▸ | NPY2R | P49146 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.37 |
| ▸ | FURIN | P09958 | 5/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | NMT2 | O60551 | 1/20 | 0.35 |
| ▸ | NMT1 | P30419 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | GART | P22102 | 1/20 | 0.33 |
| ▸ | ATIC | P31939 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20887736 | 0.92 | FAP (0.37) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL23420959 | 0.92 | FAP (0.37) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL19681467 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL21474404 | 0.91 | PTGS1 (0.45) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL27421373 | 0.91 | FAP (0.36) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL23105973 | 0.90 | PTGS1 (0.41) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL20864068 | 0.89 | NPY5R (0.35) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL18909056 | 0.89 | NPY5R (0.35) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL23106109 | 0.88 | PTGS1 (0.39) | PTGS1PTGS2NPY4RNPY5RNPY1R | |
| SCHEMBL18909077 | 0.87 | NMT1 (0.48) | NPY4RNPY5RNPY1RNPY2RNMT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11911483-B2 | Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-02-27 | — | — | US | disclosed |
| US-20210113706-A1 | MODIFIED SELF-IMMOLATING MOIETIES FOR USE IN PRODRUGS AND CONJUGATES AND METHODS OF USING AND MAKING | BRISTOL-MYERS SQUIBB COMPANY | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11911483-B2 | Modified self-immolating moieties for use in prodrugs and conjugates and methods of using and making | PAICS, UGT1A1, CYP7A1 | PTGS1 2687/4885PTGS2 3738/4885NPY4R 3701/4885 |
| US-20210113706-A1 | MODIFIED SELF-IMMOLATING MOIETIES FOR USE IN PRODRUGS AND CONJUGATES AND METHODS OF USING AND MAKING | PAICS, UGT1A1, CYP7A1 | PTGS1 2687/4885PTGS2 3738/4885NPY4R 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.