SCHEMBL2325855

SCHEMBL2325855

O=S(=O)(S)C(c1ccccc1)c1ccccc1

nearest known ligand 0.48

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.48
HTR6 P50406 1/20 0.43
SRC P12931 2/20 0.41
ALDH1A1 P00352 1/20 0.40
CYP2D6 P10635 1/20 0.39
DPP4 P27487 2/20 0.38
F2 P00734 1/20 0.38
TSHR P16473 1/20 0.38
LMNA P02545 2/20 0.37
MAPK1 P28482 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL780336 0.78 CYP2C19 (0.52) CYP2C19HTR6SRCALDH1A1CYP2D6
Potassium SCHEMBL29685977 0.76 CYP2C19 (0.50) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL9124179 0.76 CYP2C19 (0.50) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL1272692 0.74 CYP2C19 (0.48) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL496890 0.74 SRC (0.58) CYP2C19SRCALDH1A1CYP2D6TSHR
SCHEMBL5886893 0.74 CYP2C19 (0.48) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL8520306 0.74 CYP2C19 (0.48) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL3637962 0.74 CYP2C19 (0.48) CYP2C19SRCALDH1A1CYP2D6DPP4
SCHEMBL6050266 0.74 CYP2C19 (0.48) CYP2C19HTR6SRCALDH1A1CYP2D6
SCHEMBL27492041 0.74 CYP2C19 (0.48) CYP2C19HTR6SRCALDH1A1CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356182-B1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2015-05-06 EP disclosed
US-20130299736-A1 RADIATION-CURABLE COATING MATERIALS BASE SE (DE) 2013-11-14 US disclosed
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS BASF SE (DE) 2011-09-22 US disclosed
EP-2356182-A1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2011-08-17 EP disclosed
CN-101069129-B Radiation-curable coating substances BASF AG 2010-12-08 CN disclosed
US-20100126386-A1 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2010-05-27 US disclosed
WO-2010055050-A1 RADIATION CURABLE COATING MATERIALS BASF SE (DE) 2010-05-20 WO disclosed
WO-2008058885-A2 RADIATION-HARDENABLE COATING MASSES BASF SE (DE) 2008-05-22 WO disclosed
WO-2007138095-A1 USE OF STABILIZING COMPOSITIONS CONTAINING CYANINE CATIONS IN PACKAGING MATERIALS BASF SE (DE) 2007-12-06 WO disclosed
CN-101069129-A Radiation-curable coating substances BASF AG (DE) 2007-11-07 CN disclosed
EP-1820064-A2 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2007-08-22 EP disclosed
WO-2006058731-A2 RADIATION-CURABLE COATING SUBSTANCES BASF AKTIENGESELLSCHAFT (DE) 2006-06-08 WO disclosed
US-6110987-A CURED PRODUCTS HAVING AN EXCELLENT APPEARANCE WITHOUT COLORING CAUSED BY POLYMERIZATION INITIATOR SHOWA DENKO K.K. (JP) 2000-08-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110230617-A1 RADIATION-CURABLE COATING MATERIALS RAD51, MGMT, RAD54L CYP2C19 3154/4885HTR6 2274/4885SRC 2759/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.