Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.32 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23258826 | 0.84 | ELANE (0.41) | ELANEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL27018562 | 0.83 | ELANE (0.42) | ELANEMTNR1AMTNR1BBRD4SMN1; SMN2 | |
| SCHEMBL23258536 | 0.82 | PKM (0.43) | ELANEMTNR1AMTNR1BGABRA1GABRG2 | |
| SCHEMBL14839466 | 0.81 | ELANE (0.44) | ELANEMTNR1AMTNR1BGABRA1GABRG2 | |
| SCHEMBL23258559 | 0.80 | ELANE (0.38) | ELANEGABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL23258557 | 0.79 | ELANE (0.37) | ELANEMTNR1AMTNR1BGABRA1GABRG2 | |
| SCHEMBL23258561 | 0.78 | ELANE (0.44) | ELANEMTNR1AMTNR1BGABRA1GABRG2 | |
| SCHEMBL23258883 | 0.77 | ELANE (0.40) | ELANEMTNR1AMTNR1BBRD4CYP1A2 | |
| SCHEMBL7714404 | 0.76 | ELANE (0.41) | ELANEMTNR1AMTNR1BBRD4CA2 | |
| SCHEMBL15868700 | 0.76 | ELANE (0.41) | ELANEMTNR1AMTNR1BGABRA1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021076938-A1 | TROPOLONE DERIVATIVES AND TAUTOMERS THEREOF FOR IRON REGULATION IN ANIMALS | Ambys Medicines, Inc. (US) | 2021-04-22 | — | — | WO | disclosed |