Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 15/20 | 0.71 |
| ▸ | CTSV | O60911 | 2/20 | 0.69 |
| ▸ | CTSL | P07711 | 2/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.55 |
| ▸ | HRH1 | P35367 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.52 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TUBB | P07437 | 1/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29712365 | 1.00 | HRH3 (0.71) | HRH3CTSVCTSLKDM4ELMNA | |
| SCHEMBL29712363 | 0.99 | HRH3 (0.72) | HRH3CTSVCTSLKDM4ELMNA | |
| SCHEMBL23259788 | 0.99 | HRH3 (0.72) | HRH3CTSVCTSLKDM4ELMNA | |
| SCHEMBL6301198 | 0.83 | HRH3 (1.00) | HRH3KCNH2HRH1HRH4 | |
| SCHEMBL23259715 | 0.82 | CTSV (0.81) | CTSVCTSLKDM4ELMNAHPGD | |
| SCHEMBL29712383 | 0.82 | CTSV (0.81) | CTSVCTSLKDM4ELMNAHPGD | |
| SCHEMBL23259585 | 0.79 | HRH3 (0.55) | HRH3KDM4EALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL29712381 | 0.79 | HRH3 (0.55) | HRH3KDM4EALDH1A1SMN1; SMN2KCNH2 | |
| SCHEMBL23259587 | 0.78 | HRH3 (0.56) | HRH3KCNH2HRH1ADRA1AHRH4 | |
| SCHEMBL30025655 | 0.78 | HRH3 (0.56) | HRH3KCNH2HRH1ADRA1AHRH4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HANGZHOU BIO-SINCERITY PHARMA-TECH CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HANGZHOU BIO-SINCERITY PHARMA-TECH CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HANGZHOU BIO-SINCERITY PHARMA-TECH CO., LTD. (CN) | 2023-09-21 | — | — | US | disclosed |
| WO-2021072642-A1 | USE OF PHENYLQUINOLINONES AND FLAVONOID DERIVATIVES FOR TREATING NEUROPATHIC PAIN | 杭州百诚医药科技股份有限公司 | 2021-04-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230295134-A1 | USE OF PHENYLQUINOLINONE DERIVATIVE OR FLAVONOID DERIVATIVE FOR TREATING NEUROPATHIC PAIN | HRH4, HRH2, HRH1 | HRH3 7/4885CTSV 882/4885CTSL 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.