Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 14/20 | 0.58 |
| ▸ | INSR | P06213 | 6/20 | 0.52 |
| ▸ | IGF1R | P08069 | 6/20 | 0.52 |
| ▸ | ALK | Q9UM73 | 6/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23259843 | 0.94 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL23259938 | 0.91 | EGFR (0.56) | EGFRINSRIGF1RALK | |
| SCHEMBL23260568 | 0.88 | EGFR (0.64) | EGFRINSRIGF1RALK | |
| SCHEMBL24781107 | 0.86 | EGFR (0.57) | EGFR | |
| SCHEMBL24179126 | 0.85 | EGFR (0.68) | EGFRINSRIGF1RALK | |
| SCHEMBL25449051 | 0.84 | EGFR (0.67) | EGFRINSRIGF1RALK | |
| SCHEMBL23154237 | 0.83 | EGFR (0.62) | EGFR | |
| SCHEMBL23154173 | 0.83 | EGFR (0.65) | EGFRINSRIGF1RALK | |
| SCHEMBL23154183 | 0.83 | INSR (0.59) | EGFRINSRIGF1RALK | |
| SCHEMBL23154150 | 0.82 | INSR (0.57) | EGFRINSRIGF1RALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021073498-A1 | EGFR INHIBITOR, COMPOSITION, AND METHOD FOR PREPARATION THEREOF | 贝达药业股份有限公司 | 2021-04-22 | — | — | WO | disclosed |