Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 11/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 8/20 | 0.35 |
| ▸ | PDE4A | P27815 | 6/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 6/20 | 0.35 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431922 | 1.00 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264310 | 0.95 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264279 | 0.95 | PDE4B (0.34) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29431906 | 0.95 | PDE4B (0.34) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264314 | 0.94 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264311 | 0.92 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264315 | 0.91 | PDE4B (0.32) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264286 | 0.91 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29431915 | 0.91 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264313 | 0.91 | DHODH (0.34) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112707841-B | 3-N-cyclopropylmethyl-2-fluorobenzamide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-112661665-B | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2021078293-A1 | 3-N-CYCLOPROPYLMETHYL-2-FLUOROBENZAMIDE COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 南通泰禾化工股份有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-112707841-A | 3-N-cyclopropylmethyl-2-fluorobenzamide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2021-04-27 | — | — | CN | disclosed |
| WO-2021073373-A1 | AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC NANTONG CHEMICAL CO., LTD. (CN) | 2021-04-22 | — | — | WO | disclosed |
| CN-112661665-A | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2021-04-16 | — | — | CN | disclosed |