Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 12/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.38 |
| ▸ | PDE4A | P27815 | 5/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 5/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431915 | 1.00 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264305 | 0.93 | PDE4B (0.40) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23053045 | 0.92 | HDAC8 (0.36) | HDAC8GPBAR1 | |
| SCHEMBL23264274 | 0.91 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29431922 | 0.91 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264306 | 0.91 | PDE4D (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264310 | 0.90 | PDE4B (0.35) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264279 | 0.90 | PDE4B (0.34) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL29431906 | 0.90 | PDE4B (0.34) | PDE4BPDE4DPDE4APDE4CABCB11 | |
| SCHEMBL23264314 | 0.90 | PDE4B (0.38) | PDE4BPDE4DPDE4APDE4CABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112661665-B | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2021-09-14 | — | — | CN | disclosed |
| WO-2021073373-A1 | AMIDE COMPOUNDS AND PREPARATION METHOD THEREFOR AND USE THEREOF | CAC NANTONG CHEMICAL CO., LTD. (CN) | 2021-04-22 | — | — | WO | disclosed |
| CN-112661665-A | Amide compound and preparation method and application thereof | 南通泰禾化工股份有限公司 | 2021-04-16 | — | — | CN | disclosed |