Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 20/20 | 0.61 |
| ▸ | OGFRL1 | Q5TC84 | 15/20 | 0.61 |
| ▸ | OPRL1 | P41146 | 9/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.61 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL700118 | 0.92 | OPRM1 (0.63) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL699820 | 0.92 | OPRM1 (0.54) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL699732 | 0.90 | OPRM1 (0.62) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL699715 | 0.88 | OPRM1 (0.65) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| Citric Acid SCHEMBL700111 | 0.88 | OPRM1 (0.49) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL699426 | 0.87 | OPRM1 (0.58) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL700005 | 0.85 | OPRM1 (0.53) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL700162 | 0.82 | OPRM1 (0.59) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL700102 | 0.82 | OPRM1 (0.58) | OPRM1OGFRL1OPRL1OPRD1OPRK1 | |
| SCHEMBL699427 | 0.81 | OPRM1 (0.56) | OPRM1OGFRL1OPRL1OPRD1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2010531-B1 | SPIROCYCLIC CYCLOHEXANE DERIVATIVES WITH ANALGESIC PROPERTIES | GRUENENTHAL GMBH (DE) | 2011-08-17 | — | — | EP | claimed |
| EP-2010531-B1 | SPIROCYCLIC CYCLOHEXANE DERIVATIVES WITH ANALGESIC PROPERTIES | GRUENENTHAL GMBH (DE) | 2011-08-17 | — | — | EP | disclosed |