SCHEMBL23266182

SCHEMBL23266182

COc1cccc(CCCCO[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1

nearest known ligand 0.65

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ MAOB P27338 1/20 0.47
▸ SLC5A2 P31639 4/20 0.47
▸ SLC5A1 P13866 1/20 0.47
▸ SELP P16109 2/20 0.46
▸ SELPLG Q14242 1/20 0.46
▸ ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23266230 1.00 MAOB (0.47) MAOBSLC5A2SLC5A1SELPSELPLG
SCHEMBL23266308 0.89 LGALS8 (0.46) MAOBSLC5A2SLC5A1ACHE
SCHEMBL23266255 0.89 LGALS8 (0.46) MAOBSLC5A2SLC5A1ACHE
SCHEMBL23266190 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23266324 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23266326 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23350452 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23266188 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23266310 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1
SCHEMBL23266192 0.86 SLC5A1 (0.56) MAOBSLC5A2SLC5A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2022-05-10 — — US disclosed
WO-2021139621-A1 METHOD FOR PREPARING GLYCOSIDE COMPOUND 上海和黄药业有限公司 2021-07-15 — — WO disclosed
EP-3819303-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE Shanghai Hutchison Pharmaceuticals Limited (CN) 2021-05-12 — — EP disclosed
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE SHANGHAI HUTCHISON PHARMACEUTICALS LIMITED (CN) 2021-04-22 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11325937-B2 Glycoside compound and preparation method therefor, composition, application, and intermediate VEGFA, FLT4, FLT1 MAOB 1432/4885SLC5A2 897/4885SLC5A1 431/4885
US-20210115082-A1 GLYCOSIDE COMPOUND AND PREPARATION METHOD THEREFOR, COMPOSITION, APPLICATION, AND INTERMEDIATE VEGFA, FLT4, FLT1 MAOB 1432/4885SLC5A2 897/4885SLC5A1 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback