Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.42 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.42 |
| ▸ | CHRNG | P07510 | 1/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.42 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.42 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.42 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.42 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.42 |
| ▸ | CHRND | Q07001 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HTR2B | P41595 | 3/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 7/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27896146 | 0.84 | HTR2A (0.49) | CHRNB2CHRNB4CHRNA3CHRNA4HTR2A | |
| SCHEMBL12035558 | 0.81 | KDM1A (0.35) | RIPK1KDM1AKDM1B | |
| SCHEMBL15668936 | 0.80 | KDM1A (0.63) | SLC6A2SLC6A4SLC6A3KDM1A | |
| SCHEMBL21236289 | 0.79 | SLC6A3 (0.43) | SLC6A2SLC6A4SLC6A3CHRNA1CHRNG | |
| SCHEMBL2320349 | 0.78 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL16802361 | 0.75 | KDM1A (0.62) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL14900233 | 0.75 | KDM1A (0.62) | HTR2AHTR2CHTR2BKDM1AKCNH2 | |
| SCHEMBL11965121 | 0.74 | HTR2A (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL2359931 | 0.74 | HTR2A (0.44) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C | |
| SCHEMBL2360390 | 0.74 | KDM1A (0.52) | SLC6A2SLC6A4SLC6A3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094890-A1 | PHENYLALANINE DERIVATIVES AND THEIR USE AS NON-PEPTIDE GLP-1 RECEPTOR MODULATORS | ARGUSINA INC. (US) | 2011-08-11 | — | — | WO | disclosed |