Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.78 |
| ▸ | NPC1 | O15118 | 2/20 | 0.78 |
| ▸ | RAB9A | P51151 | 2/20 | 0.78 |
| ▸ | POLB | P06746 | 1/20 | 0.78 |
| ▸ | SCP2 | P22307 | 1/20 | 0.63 |
| ▸ | GPR84 | Q9NQS5 | 10/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.43 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15398206 | 0.96 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL15398222 | 0.96 | MEN1 (0.78) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL23244676 | 0.91 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL23244637 | 0.88 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9APOLB | |
| Nile Red SCHEMBL29373685 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| Nile Red SCHEMBL49047 | 0.88 | MEN1 (1.00) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL23244667 | 0.87 | MEN1 (0.70) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL23266940 | 0.85 | MEN1 (0.74) | MEN1KMT2ANPC1RAB9APOLB | |
| Nile Red SCHEMBL28703996 | 0.85 | MEN1 (0.93) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL23244628 | 0.84 | MEN1 (0.67) | MEN1KMT2ANPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210115000-A1 | NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210115000-A1 | NILE RED DERIVATIVES FOR IMPROVED RATIOMETRIC IMAGING FOR NERVE SPECIFIC CONTRAST | FABP4, LRBA, FABP7 | MEN1 3010/4885KMT2A 4468/4885NPC1 249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.