Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 7/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.52 |
| ▸ | MELK | Q14680 | 1/20 | 0.51 |
| ▸ | PTK2 | Q05397 | 7/20 | 0.47 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 4/20 | 0.42 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.41 |
| ▸ | HPGDS | O60760 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29873956 | 0.95 | BCL6 (0.48) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL23249919 | 0.95 | BCL6 (0.48) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL23267715 | 0.94 | BCL6 (0.49) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL23266803 | 0.94 | BCL6 (0.48) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL31595441 | 0.94 | BCL6 (0.59) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL31595571 | 0.93 | BCL6 (0.49) | BCL6NCOR2MELKPTK2BTK | |
| SCHEMBL23266265 | 0.93 | BCL6 (0.49) | BCL6NCOR2MELKPTK2BTK | |
| SCHEMBL31595516 | 0.92 | BCL6 (0.58) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL31595569 | 0.92 | BCL6 (0.58) | BCL6NCOR2MELKPTK2CHRM4 | |
| SCHEMBL23267932 | 0.92 | BCL6 (0.52) | BCL6NCOR2MELKPTK2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |