Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.55 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.50 |
| ▸ | MELK | Q14680 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23267168 | 0.90 | BCL6 (0.57) | BCL6NCOR2MELK | |
| SCHEMBL23267496 | 0.89 | BCL6 (0.56) | BCL6NCOR2MELK | |
| SCHEMBL23267200 | 0.87 | BCL6 (0.61) | BCL6NCOR2MELK | |
| SCHEMBL23267516 | 0.85 | BCL6 (0.59) | BCL6NCOR2MELK | |
| SCHEMBL23267483 | 0.85 | BCL6 (0.54) | BCL6NCOR2MELK | |
| SCHEMBL23267481 | 0.83 | BCL6 (0.57) | BCL6NCOR2MELK | |
| SCHEMBL23267253 | 0.81 | BCL6 (0.76) | BCL6NCOR2MELK | |
| SCHEMBL23268066 | 0.81 | BCL6 (0.56) | BCL6NCOR2MELK | |
| SCHEMBL23268061 | 0.81 | BCL6 (0.58) | BCL6NCOR2MELK | |
| SCHEMBL23267844 | 0.81 | BCL6 (0.66) | BCL6NCOR2MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |