Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 20/20 | 0.56 |
| ▸ | NCOR2 | Q9Y618 | 4/20 | 0.49 |
| ▸ | MELK | Q14680 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23267168 | 0.91 | BCL6 (0.57) | BCL6NCOR2MELK | |
| SCHEMBL23267495 | 0.89 | BCL6 (0.55) | BCL6NCOR2MELK | |
| SCHEMBL23267200 | 0.88 | BCL6 (0.61) | BCL6NCOR2MELK | |
| SCHEMBL23267525 | 0.85 | BCL6 (0.58) | BCL6NCOR2MELK | |
| SCHEMBL23267490 | 0.84 | BCL6 (0.54) | BCL6NCOR2MELK | |
| SCHEMBL23267486 | 0.83 | BCL6 (0.56) | BCL6NCOR2MELK | |
| SCHEMBL23267485 | 0.82 | BCL6 (0.49) | BCL6NCOR2MELK | |
| SCHEMBL23267102 | 0.81 | BCL6 (0.48) | BCL6NCOR2MELK | |
| SCHEMBL23267497 | 0.81 | BCL6 (0.66) | BCL6NCOR2MELK | |
| SCHEMBL23267489 | 0.81 | BCL6 (0.55) | BCL6NCOR2MELK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |