Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 3/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.51 |
| ▸ | CDK2 | P24941 | 2/20 | 0.51 |
| ▸ | KDR | P35968 | 2/20 | 0.51 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.51 |
| ▸ | CDK4 | P11802 | 1/20 | 0.51 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.51 |
| ▸ | CCND1 | P24385 | 1/20 | 0.51 |
| ▸ | CCND3 | P30281 | 1/20 | 0.51 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.51 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.51 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.51 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.51 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2330481 | 0.89 | KDR (0.46) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2321693 | 0.88 | CDK1 (0.65) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2327157 | 0.86 | SMN1; SMN2 (0.50) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2323869 | 0.86 | CDK2 (0.52) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2325784 | 0.85 | NPC1 (0.58) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL13140861 | 0.83 | BCL6 (0.48) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL6476844 | 0.83 | BCL6 (0.55) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL27112183 | 0.83 | CAMK2D (0.51) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2330431 | 0.83 | KDR (0.49) | CDK1CDK5CDK5R1CDK2KDR | |
| SCHEMBL2323714 | 0.83 | CDK1 (0.49) | CDK1CDK5CDK5R1CDK2KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | claimed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | claimed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | claimed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | claimed |
| CN-102239160-A | Substituted (pyridyl) -azinylamine derivatives as fungicides | BAYER CROPSCIENCE SA | 2011-11-09 | — | — | CN | disclosed |
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-09-08 | — | — | US | disclosed |
| EP-2356107-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| WO-2010055077-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | BAYER CROPSCIENCE SA (FR) | 2010-05-20 | — | — | WO | disclosed |
| US-20050130968-A1 | Fungicidal 4-(2-aminopyridin-4-yl)-N-phenyl-1,3,5-triazin-2-amine derivatives | IRVINE NICHOLAS M (US) | 2005-06-16 | — | — | US | disclosed |
| WO-2005033095-A1 | FUNGICIDAL 4-(2-AMINOPYRIDIN-4-YL)-N-PHENYL-1,3,5-TRIAZIN-2-AMINE DERIVATIVES | DOW AGROSCIENCES LLC (US) | 2005-04-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110218188-A1 | SUBSTITUTED (PYRIDYL)-AZINYLAMINE DERIVATIVES AS FUNGICIDES | CYP1A1, CYP1A2, PNPO | CDK1 206/4885CDK5 1184/4885CDK5R1 1284/4885 |
| US-20050130968-A1 | Fungicidal 4-(2-aminopyridin-4-yl)-N-phenyl-1,3,5-triazin-2-amine derivatives | AADAC, DDT, TH | CDK1 2757/4885CDK5 1687/4885CDK5R1 1570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.