Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 19/20 | 0.70 |
| ▸ | NCOR2 | Q9Y618 | 6/20 | 0.70 |
| ▸ | MELK | Q14680 | 1/20 | 0.69 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.56 |
| ▸ | BCL6B | Q8N143 | 1/20 | 0.56 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20284344 | 0.92 | BCL6 (0.70) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267064 | 0.91 | BCL6 (0.78) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL31554691 | 0.91 | BCL6 (0.78) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23250073 | 0.91 | BCL6 (0.67) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL29874209 | 0.91 | BCL6 (0.67) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267253 | 0.89 | BCL6 (0.76) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL31554638 | 0.89 | BCL6 (0.75) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267179 | 0.89 | BCL6 (0.74) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL20284725 | 0.89 | BCL6 (0.79) | BCL6NCOR2MELKCHRM4BCL6B | |
| SCHEMBL23267872 | 0.88 | BCL6 (0.64) | BCL6NCOR2MELKCHRM4BCL6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |