Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 5/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.45 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.45 |
| ▸ | PTK2 | Q05397 | 15/20 | 0.42 |
| ▸ | HPGDS | O60760 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31595385 | 1.00 | CRBN (0.46) | CRBNBTKDDB1IKZF3PTK2 | |
| SCHEMBL31595777 | 0.90 | CRBN (0.53) | CRBNBTKPTK2 | |
| SCHEMBL31444700 | 0.83 | CRBN (0.47) | CRBNBTKDDB1PTK2 | |
| SCHEMBL31595331 | 0.83 | BCL6 (0.58) | — | |
| SCHEMBL31595552 | 0.83 | BCL6 (0.58) | — | |
| SCHEMBL23267348 | 0.82 | BCL6 (0.54) | PTK2 | |
| SCHEMBL29874109 | 0.82 | BCL6 (0.54) | PTK2 | |
| SCHEMBL23250042 | 0.82 | BCL6 (0.54) | PTK2 | |
| SCHEMBL31595669 | 0.82 | BCL6 (0.54) | PTK2 | |
| SCHEMBL23266802 | 0.80 | BCL6 (0.47) | PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021077010-A1 | BIFUNCTIONAL MOLECULES CONTAINING AN E3 UBIQUITINE LIGASE BINDING MOIETY LINKED TO A BCL6 TARGETING MOIETY | ARVINAS OPERATIONS, INC. (US) | 2021-04-22 | — | — | WO | disclosed |