Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 3/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.42 |
| ▸ | KLK1 | P06870 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20027730 | 0.90 | CAPN1 (0.55) | DCAF1CAPN1CTSKCTSL | |
| SCHEMBL20027878 | 0.90 | CAPN1 (0.55) | DCAF1CAPN1CTSKCTSL | |
| SCHEMBL20028241 | 0.84 | DCAF1 (0.50) | DCAF1CAPN1CTSKCTSLKMT2A | |
| SCHEMBL20027909 | 0.82 | DCAF1 (0.53) | DCAF1POLBCAPN1CTSKCTSL | |
| SCHEMBL21854195 | 0.81 | CAPN1 (0.48) | DCAF1CAPN1CTSKCTSLMAPT | |
| SCHEMBL20027846 | 0.81 | CAPN1 (0.48) | DCAF1CAPN1CTSKCTSLMAPT | |
| SCHEMBL20028183 | 0.80 | CAPN1 (0.47) | DCAF1CAPN1CTSKCTSLKMT2A | |
| SCHEMBL20027852 | 0.80 | CAPN1 (0.47) | DCAF1CAPN1CTSKCTSLKMT2A | |
| SCHEMBL22897244 | 0.80 | DCAF1 (0.46) | DCAF1POLBCTSKCTSLMEN1 | |
| SCHEMBL24862949 | 0.77 | CAPN1 (0.59) | POLBCAPN1ACECTSKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210113560-A1 | METHOD OF TREATING FIBROTIC DISEASE | BLADE THERAPEUTICS INC (US) | 2021-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210113560-A1 | METHOD OF TREATING FIBROTIC DISEASE | CAPN9, CAPNS1, CAPN1 | DCAF1 2787/4885POLB 1986/4885CAPN1 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.