SCHEMBL2327437

SCHEMBL2327437

CCCCCCc1ccccc1C(=O)NC(CS(=O)(=O)O)C(=O)O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYSLTR2 Q9NS75 6/20 0.41
CYSLTR1 Q9Y271 6/20 0.41
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
SLC16A3 O15427 2/20 0.40
PYGL P06737 1/20 0.40
CA2 P00918 1/20 0.40
BID P55957 3/20 0.40
MCL1 Q07820 3/20 0.40
BCL2L1 Q07817 2/20 0.40
BAK1 Q16611 2/20 0.40
KAT8 Q9H7Z6 2/20 0.40
NAAA Q02083 2/20 0.40
PPARG P37231 1/20 0.40
PPARA Q07869 1/20 0.40
EP300 Q09472 1/20 0.40
KAT2A Q92830 1/20 0.40
KAT2B Q92831 1/20 0.40
KAT5 Q92993 1/20 0.40
SAE1 Q9UBE0 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2328071 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2329721 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2327440 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2328069 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2329726 1.00 CYSLTR2 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2326571 0.99 CA12 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2326565 0.99 CA12 (0.41) CYSLTR2CYSLTR1CA12CA9SLC16A3
SCHEMBL2323901 0.95 CA2 (0.41) CA12CA9PYGLCA2
SCHEMBL2323895 0.95 CA2 (0.41) CA12CA9PYGLCA2
SCHEMBL2327518 0.90 HTT (0.40) CA12CA9PYGLCA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 CYSLTR2 2031/4885CYSLTR1 1886/4885CA12 4455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.