Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | JMJD6 | Q6NYC1 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23275622 | 0.79 | NPC1 (0.43) | CYP2C19CYP2C9PIK3CACYP1A2CYP2D6 | |
| SCHEMBL16973709 | 0.79 | CYP2C19 (0.43) | CYP2C19CYP2C9CYP1A2CYP2D6NPSR1 | |
| SCHEMBL12571588 | 0.79 | MAP4K4 (0.45) | CYP2C19CYP2C9LMNAPIK3CARAB9A | |
| SCHEMBL23275666 | 0.77 | JAK3 (0.43) | LMNASLC34A1MAPTKDM4EALDH1A1 | |
| SCHEMBL23275704 | 0.77 | PIK3CA (0.40) | PIK3CANPSR1JMJD6MAPTRAB9A | |
| SCHEMBL15578611 | 0.76 | ALKBH1 (0.48) | LMNARAB9A | |
| SCHEMBL31023588 | 0.76 | MAPT (0.49) | PIK3CAJMJD6MAPTEGLN1 | |
| SCHEMBL12571585 | 0.75 | NPC1 (0.46) | CYP2C19CYP2C9PIK3CACYP1A2CYP2D6 | |
| SCHEMBL2159904 | 0.74 | EGLN1 (0.64) | LMNAPIK3CAMAPTRAB9AKDM4E | |
| SCHEMBL30535434 | 0.74 | EGLN1 (0.64) | LMNAPIK3CAMAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078020-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078020-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| CN-110734428-A | small molecule compounds | 嘉兴特科罗生物科技有限公司 | 2020-01-31 | — | — | CN | disclosed |