ALKBH1 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL358277	0.57	9/20
SCHEMBL4531709	0.49	9/20
SCHEMBL2864450	0.50	8/20
SCHEMBL4762197	0.43	8/20
SCHEMBL2148413	0.38	8/20
SCHEMBL2861439	0.51	7/20
SCHEMBL2861126	0.54	6/20
SCHEMBL2859635	0.53	6/20
SCHEMBL1198990	0.51	6/20
Hydrochloric Acid (SCHEMBL2938655)	0.47	6/20
SCHEMBL1414655	0.44	6/20
SCHEMBL553831	0.43	6/20
SCHEMBL370482	0.41	6/20
SCHEMBL4022892	0.38	6/20
SCHEMBL2088870	0.34	6/20
SCHEMBL4703265	0.51	5/20
SCHEMBL5883689	0.51	5/20
SCHEMBL3753454	0.47	5/20
Hydrochloric Acid (SCHEMBL1921639)	0.47	5/20
SCHEMBL3777154	0.45	5/20

Clinical trials — most relevant to ALKBH1 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Acelarin First Line Randomised Pancreatic Study	PHASE2/PHASE3	SUSPENDED
Therapeutic Safety and Efficacy of REP 2139 (REP 9AC') in HBV Infected Patients	PHASE1/PHASE2	COMPLETED
Phase 1/ Phase 2 Study to Assess Safety and Efficacy of Orally Administered JBI-802 in Subjects With Myeloproliferative Neoplasms (MPN) and Myelodysplastic/Myeloproliferative Neoplasms (MDS/MPN) With Thrombocytosis	PHASE1/PHASE2	RECRUITING
Clinical Study of EBV-LMP1 Targeted DNAzyme to Treat Nasopharyngeal Carcinoma	PHASE1/PHASE2	COMPLETED
A Phase 1 Safety and Dose Finding Study of GLIX1 in Adults With Recurrent or Progressive High-grade Glioma	PHASE1	RECRUITING
Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors	PHASE1	COMPLETED
Epitranscriptomic Blood Biomarkers for Coronary Artery Disease - A Prospective Cohort Study (IHD-EPITRAN)	nan	UNKNOWN
Expression of TET1 Gene in Acute Leukaemia	nan	UNKNOWN
The Molecular Pathogenesis Study of Cataract	nan	UNKNOWN
Investigation of the Genetic and Environmental Causes of Autism: a Multi-Center Study	nan	NOT_YET_RECRUITING
Investigation of ADA Enzyme Deficiency	nan	UNKNOWN
Prognosis of METTL-14 in Endometrial Carcinoma	nan	NOT_YET_RECRUITING
Molecular Profiling for Risk Stratification in Appendiceal Cancer	nan	RECRUITING
Observational Study Evaluating the Prevalence of Enzyme Deficiency in Pulmonology Clinics (ADA)	nan	UNKNOWN
Impact Of Choline in Patients With NAFLD	nan	UNKNOWN
Using the Epitranscriptome to Diagnose and Treat Gliomas	nan	RECRUITING
Efficacy of Essential Phospholipid Versus Betaine HCL/L-Glutamic Acid in MAFLD	nan	NOT_YET_RECRUITING
DNA Adductomics for Colorectal Cancer Investigation	nan	UNKNOWN
A Proof of Concept Study for the DNA Repair Driven by the Mesenchymal Stem Cells in Critical COVID-19 Patients	nan	COMPLETED
Proof of Concept Creatine Supplementation for Homocystinuria Study	nan	ACTIVE_NOT_RECRUITING
Hydroxymethylation, Incident Type 2 Diabetes and Incident Obesity	nan	UNKNOWN
Studying Tumor Samples From Young Patients With Neuroblastoma	nan	COMPLETED
The Role of FTO Gene Polymorphism and Insulin Preparation in Obesity in Children With Type 1 Diabetes Mellitus	nan	COMPLETED
ADAR1 Expression Level in Rectal Cancer	nan	RECRUITING
Adenosylmethionine Metabolism in Human Inflammation	nan	UNKNOWN
Investigation of Methylation of EGFR in the Response of the Cetuximab in Metastatic Colorectal Cancer Patients	nan	COMPLETED
Impact of Weight Loss on the Human Sperm Epitranscriptome	nan	ACTIVE_NOT_RECRUITING
SMYD3-Driven Metabolic Rewiring in Colorectal Liver Metastases	nan	NOT_YET_RECRUITING
Lung Cancer Diagnosis by Detecting Epigenetic Imprinting Alterations in Bronchoalveolar Lavage	nan	UNKNOWN
Infrared Wraps Effect on Oxygenation of Diabetics Arm, Feet and Lower Leg	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a ALKBH1 binder may also engage these)

Protein	Name	Similarity
P0CB42	—	1.000	P0CB42 →
KDM5B	Lysine-specific demethylase 5B	0.992	landscape →
KDM5D	Lysine-specific demethylase 5D	0.991	landscape →
A3KGZ2	—	0.991	A3KGZ2 →
Q5XUN4	—	0.990	Q5XUN4 →
Q5F3R2	—	0.990	Q5F3R2 →
Q9D5Z5	—	0.990	Q9D5Z5 →
DHX29	ATP-dependent RNA helicase DHX29	0.990	landscape →
F4KH86	—	0.989	F4KH86 →
Q9D3R6	—	0.989	Q9D3R6 →
Q62240	—	0.989	Q62240 →
Q9Z2R9	—	0.989	Q9Z2R9 →
O60066	—	0.989	O60066 →
D3YWQ0	—	0.989	D3YWQ0 →
KDM4E	Lysine-specific demethylase 4E	0.989	landscape →
A1L252	—	0.989	A1L252 →
Q9CQ04	—	0.988	Q9CQ04 →
KAT8	Histone acetyltransferase KAT8	0.988	landscape →
P0DO23	—	0.988	P0DO23 →
Q9LX30	—	0.988	Q9LX30 →
F4IF36	—	0.988	F4IF36 →
Q6NXH8	—	0.988	Q6NXH8 →
B5E0H4	—	0.988	B5E0H4 →
A8E7C5	—	0.988	A8E7C5 →
Q8BMD7	—	0.988	Q8BMD7 →
Q8BJM7	—	0.988	Q8BJM7 →
Q5I3B2	—	0.988	Q5I3B2 →
Q4R8E0	—	0.988	Q4R8E0 →
Q3T9Z9	—	0.988	Q3T9Z9 →
Q5E9U4	—	0.988	Q5E9U4 →