Methane

Methane

SCHEMBL2327641

C.C.Oc1c2ccccc2cc2ccccc12

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN22 Q9Y2R2 1/20 0.54
TRPM4 Q8TD43 1/20 0.54
NQO2 P16083 1/20 0.52
ALDH1A1 P00352 3/20 0.50
HSD17B10 Q99714 2/20 0.50
CYP1A2 P05177 2/20 0.50
KDM4E B2RXH2 2/20 0.50
MEN1 O00255 2/20 0.50
HPGD P15428 2/20 0.50
KMT2A Q03164 2/20 0.50
CASP6 P55212 1/20 0.50
GLA P06280 1/20 0.50
CYP2C19 P33261 1/20 0.50
NQO1 P15559 1/20 0.48
ALOX5 P09917 1/20 0.48
HIF1A Q16665 1/20 0.48
CYP1B1 Q16678 1/20 0.48
HTR2A P28223 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
LDHA P00338 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methane SCHEMBL155047 1.00 PTPN22 (0.54) PTPN22TRPM4NQO2ALDH1A1HSD17B10
SCHEMBL437148 0.97 PTPN22 (0.56) PTPN22TRPM4NQO2ALDH1A1HSD17B10
Hydrogen Sulfide SCHEMBL27992660 0.94 PTPN22 (0.54) PTPN22TRPM4NQO2ALDH1A1HSD17B10
SCHEMBL29180044 0.94 PTPN22 (0.54) PTPN22TRPM4NQO2ALDH1A1HSD17B10
Ethane SCHEMBL240652 0.92 PTPN22 (0.52) PTPN22TRPM4NQO2ALDH1A1HSD17B10
Propane SCHEMBL243407 0.90 PTPN22 (0.50) PTPN22TRPM4NQO2ALDH1A1HSD17B10
SCHEMBL11757019 0.87 PTPN22 (0.48) PTPN22TRPM4NQO2ALDH1A1HSD17B10
Methane SCHEMBL7938140 0.87 CYP1A2 (0.52) PTPN22TRPM4NQO2ALDH1A1HSD17B10
SCHEMBL31320895 0.85 PTPN22 (0.46) PTPN22TRPM4NQO2ALDH1A1HSD17B10
Butane SCHEMBL241215 0.85 PTPN22 (0.46) PTPN22TRPM4NQO2ALDH1A1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356177-A1 AN ANTIREFLECTIVE COATING COMPOSITION COMPRISING FUSED AROMATIC RINGS AZ Electronic Materials USA Corp. (US) 2011-08-17 EP disclosed
US-20100151392-A1 ANTIREFLECTIVE COATING COMPOSITIONS RAHMAN M DALIL 2010-06-17 US disclosed
WO-2010055374-A1 AN ANTIREFLECTIVE COATING COMPOSITION COMPRISING FUSED AROMATIC RINGS AZ ELECTRONICS MATERIALS USA CORP. (US) 2010-05-20 WO disclosed
US-20100119979-A1 Antireflective Coating Composition Comprising Fused Aromatic Rings AZ ELECTRONIC MATERIALS USA CORP. 2010-05-13 US disclosed