Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 20/20 | 0.59 |
| ▸ | JAK1 | P23458 | 20/20 | 0.59 |
| ▸ | TYK2 | P29597 | 20/20 | 0.59 |
| ▸ | JAK3 | P52333 | 5/20 | 0.56 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | STAT1 | P42224 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23276950 | 0.88 | TYK2 (0.56) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276971 | 0.84 | JAK2 (0.60) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276732 | 0.84 | JAK2 (0.62) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL23276897 | 0.83 | JAK2 (0.58) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276888 | 0.82 | JAK2 (0.57) | JAK2JAK1TYK2JAK3 | |
| SCHEMBL28657664 | 0.81 | JAK1 (0.70) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276749 | 0.80 | JAK2 (0.57) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL23276626 | 0.80 | JAK2 (0.56) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL22856256 | 0.80 | JAK2 (0.55) | JAK2JAK1TYK2JAK3KDR | |
| SCHEMBL29567036 | 0.80 | JAK2 (0.55) | JAK2JAK1TYK2JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220411408-A1 | Small Molecule Compound | TECHNODERMA MEDICINES INC. (CN) | 2022-12-29 | — | — | US | disclosed |
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078022-A1 | SMALL MOLECULE COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220411408-A1 | Small Molecule Compound | JAK1, JAK2, TYK2 | JAK2 2/4885JAK1 1/4885TYK2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.