Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 20/20 | 0.56 |
| ▸ | JAK2 | O60674 | 19/20 | 0.56 |
| ▸ | JAK1 | P23458 | 19/20 | 0.56 |
| ▸ | JAK3 | P52333 | 5/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.52 |
| ▸ | STAT1 | P42224 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23276875 | 0.88 | JAK2 (0.59) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23276732 | 0.88 | JAK2 (0.62) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL23276749 | 0.84 | JAK2 (0.57) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23299669 | 0.81 | JAK2 (0.61) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23276839 | 0.80 | JAK2 (0.56) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23299641 | 0.80 | JAK1 (0.57) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23276971 | 0.80 | JAK2 (0.60) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL23276888 | 0.79 | JAK2 (0.57) | TYK2JAK2JAK1JAK3 | |
| SCHEMBL23299650 | 0.79 | TYK2 (0.60) | TYK2JAK2JAK1JAK3KDR | |
| SCHEMBL28657664 | 0.79 | JAK1 (0.70) | TYK2JAK2JAK1JAK3KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021078021-A1 | SMALL MOLECULAR COMPOUND | 嘉兴特科罗生物科技有限公司 | 2021-04-29 | — | — | WO | disclosed |