Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL736786 | 1.00 | KDM4E (0.37) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL16705148 | 0.92 | KDM4E (0.38) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL16704804 | 0.92 | KDM4E (0.38) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL14434848 | 0.84 | KDM4E (0.39) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL4401217 | 0.84 | KDM4E (0.39) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL18587123 | 0.82 | KDM4E (0.41) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL13443362 | 0.81 | KDM4E (0.40) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL123010 | 0.81 | KDM4E (0.40) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL22604704 | 0.81 | KDM4E (0.38) | KDM4ETDP1ALDH1A1LMNAEPHX2 | |
| SCHEMBL14544703 | 0.81 | KDM4E (0.40) | KDM4ETDP1ALDH1A1LMNAEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2533636-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | Mapi Pharma Limited (IL) | 2012-12-19 | — | — | EP | disclosed |
| WO-2011099010-A1 | PREPARATION OF BENZOFURANS AND USE THEREOF AS SYNTHETIC INTERMEDIATES | MAPI PHARMA HOLDINGS (CYPRUS) LIMITED (CY) | 2011-08-18 | — | — | WO | disclosed |