Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704804 | 1.00 | KDM4E (0.38) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL2327752 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL736786 | 0.92 | KDM4E (0.37) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL21646820 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL5358221 | 0.83 | ALDH1A1 (0.42) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL6537287 | 0.83 | KDM4E (0.41) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL457240 | 0.78 | KDM4E (0.41) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL13443362 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL14544703 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1PKMMAPTMAPK1 | |
| SCHEMBL13714698 | 0.78 | KDM4E (0.40) | KDM4EALDH1A1PKMMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029457-B2 | Silica-supported oligomeric hybrid materials | THE UNIVERSITY OF KANSAS (US) | 2015-05-12 | — | — | US | disclosed |