SCHEMBL23278043

SCHEMBL23278043

C[C@]1(OCc2ccccc2)C(O)(c2cnc3c(N)nc(S(C)(=O)=O)nn23)O[C@@H]2C(OCc3ccccc3)[C@@]21OCc1ccccc1

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TLR7 Q9NYK1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19997433 1.00 TLR7 (0.31) TLR7
SCHEMBL19997394 0.91 — —
SCHEMBL24168593 0.90 DCPS (0.31) —
SCHEMBL20380391 0.87 TLR7 (0.30) TLR7
SCHEMBL19997428 0.87 — —
SCHEMBL19997395 0.87 — —
SCHEMBL19997439 0.84 TNK2 (0.36) —
SCHEMBL12243231 0.81 HSPA5 (0.33) TLR7
SCHEMBL20380388 0.81 TLR7 (0.32) TLR7
SCHEMBL19997384 0.79 — —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10988498-B2 Processes and intermediates for the preparation of 1′-substituted carba-nucleoside analogs GILEAD SCIENCES, INC. (US) 2021-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10988498-B2 Processes and intermediates for the preparation of 1′-substituted carba-nucleoside analogs PNP, TYMP, CDA TLR7 2212/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback