Biphenyl

Biphenyl

SCHEMBL2327892

CO[C@H](NC(CS)C(=O)O)c1ccccc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
MME P08473 10/20 0.44
ACE2 Q9BYF1 1/20 0.42
KMT2A Q03164 1/20 0.41
PTGS2 P35354 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10336179 0.97 MME (0.46) MMEKMT2APTGS2
SCHEMBL27873592 0.97 MME (0.46) MMEKMT2APTGS2
Hydrochloric Acid SCHEMBL27734969 0.95 MME (0.45) MMEKMT2A
Biphenyl SCHEMBL2328203 0.88 MME (0.42) MMEACE2KMT2APTGS2
SCHEMBL28141556 0.84 MME (0.46) MME
SCHEMBL9752562 0.78 APAF1 (0.56) MMEKMT2A
SCHEMBL7944349 0.78 APAF1 (0.56) MMEKMT2A
SCHEMBL7620487 0.78 APAF1 (0.56) MMEKMT2A
SCHEMBL14935643 0.77 MME (0.47) MMEKMT2A
SCHEMBL21274600 0.77 MME (0.47) MMEKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2356979-B1 ANTI-WRINKLE AGENTS POLA CHEM IND INC (JP) 2017-10-25 EP disclosed
EP-3173063-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2017-05-31 EP disclosed
US-8835498-B2 Anti-wrinkle agents POLA CHEMICAL INDUSTRIES INC. (JP) 2014-09-16 US disclosed
US-20110245343-A1 ANTI-WRINKLE AGENTS POLA CHEMICAL INDUSTRIES INC. (JP) 2011-10-06 US disclosed
EP-2356979-A1 ANTI-WRINKLE AGENTS Pola Chemical Industries Inc. (JP) 2011-08-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110245343-A1 ANTI-WRINKLE AGENTS GLA, H1-4, H1-3 MME 4624/4885ACE2 4402/4885KMT2A 3153/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.